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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAH
All Species:
20.61
Human Site:
S300
Identified Species:
41.21
UniProt:
P16930
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16930
NP_000128.1
419
46374
S300
Y
T
F
D
I
N
L
S
V
N
L
K
G
E
G
Chimpanzee
Pan troglodytes
XP_001155476
421
46561
S302
Y
T
F
D
I
N
L
S
V
N
L
K
G
E
G
Rhesus Macaque
Macaca mulatta
XP_001109382
419
46350
S300
Y
T
F
D
I
N
L
S
V
A
L
K
G
E
G
Dog
Lupus familis
XP_852646
406
45079
E287
A
R
D
I
Q
K
W
E
Y
V
P
L
G
P
F
Cat
Felis silvestris
Mouse
Mus musculus
P35505
419
46085
S300
Y
T
F
D
I
N
L
S
V
S
L
K
G
E
G
Rat
Rattus norvegicus
P25093
419
45957
S300
Y
T
F
D
I
N
L
S
V
A
L
K
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413855
419
46530
F300
Y
T
F
D
I
N
L
F
V
A
I
K
G
E
G
Frog
Xenopus laevis
NP_001080458
420
46648
C300
Y
R
F
D
I
N
L
C
V
C
I
Q
G
K
G
Zebra Danio
Brachydanio rerio
NP_955895
348
38736
V233
N
I
N
L
F
V
S
V
K
G
E
G
M
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524830
417
46453
L297
P
F
N
F
D
I
N
L
E
V
S
L
K
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509083
418
46026
A302
F
T
L
D
I
N
L
A
V
S
I
R
P
E
G
Sea Urchin
Strong. purpuratus
XP_787535
389
42602
T272
F
N
F
D
I
S
I
T
A
A
V
K
G
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.9
75.8
N.A.
89
88.5
N.A.
N.A.
80.1
74.5
62.5
N.A.
60.3
N.A.
64.4
63
Protein Similarity:
100
99
98
79.7
N.A.
95.2
94.2
N.A.
N.A.
89.2
83.8
72.3
N.A.
73.7
N.A.
76.8
75.1
P-Site Identity:
100
100
93.3
6.6
N.A.
93.3
93.3
N.A.
N.A.
80
60
0
N.A.
0
N.A.
53.3
33.3
P-Site Similarity:
100
100
93.3
6.6
N.A.
100
93.3
N.A.
N.A.
86.6
80
0
N.A.
0
N.A.
86.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
9
34
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
75
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
9
0
0
59
17
% E
% Phe:
17
9
67
9
9
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
9
75
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
75
9
9
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
0
0
59
9
9
0
% K
% Leu:
0
0
9
9
0
0
67
9
0
0
42
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
9
17
0
0
67
9
0
0
17
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
9
0
9
17
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
0
0
0
0
0
9
9
42
0
17
9
0
0
0
0
% S
% Thr:
0
59
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
9
67
17
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
59
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _